Authorities say the explosion happened around 2:30 p.m. Friday and the force blew out the windows and bay doors.
Officials say the building on Westview Drive is still structurally intact. Authorities say the man who was injured is being evaluated at the scene and has not been hospitalized.
The nature of the man's injuries was not immediately clear and officials are not yet sure if he is affiliated with the college.
The Morehouse College campus is part of the Atlanta University Center consortium, which includes Clark Atlanta University and Spelman College.